Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity
Gary A. Silverman, David A. Lomas
Massive thrombosis or bleeding, hereditary angioedema, Alzheimer's disease, diabetic angiopathy and tumor invasion are some of the human diseases associated with serpins. In addition, mutations that alter serpin conformations (the serpinopathies) lead to lung disease, cirrhosis and a form of familial dementia. The goal of this text is to present the current knowledge on the molecular and cellular basis of serpins and their diseases.
Կատեգորիաներ:
Տարի:
2007
Հրատարակում:
1
Հրատարակչություն:
World Scientific Publishing Company
Լեզու:
english
Էջեր:
672
ISBN 10:
9812707549
ISBN 13:
9789812707543
Ֆայլ:
PDF, 5.73 MB
IPFS:
,
english, 2007